May significant difference almost 50% FPS sa game performance at 1080p low setting. Make sure lang na fully compatible sa motherboard at CPU. For example ung CPU ba support nia ang PCIe 3.0x16 lanes and ung GPU also has PCIe 3.0x16 lanes electrically. Ung motherboard ba has PCIe 3.0x16 lanes also available. Kung may naiba for example ung motherboard only support PCIe 2.0 x8, then there is a possibility na di gaanong significant ang upgrade lalo na sa mga high graphics games.
Download mo yung techpowerup gpu-z then--> run mo yung pci render test to check kung ano ang pcie lanes na gamit ng iyong computer if 3.0x16 I would say there is a greater change na may significant upgrade otherwise i'm not sure.